Mysthera Therapeutics launches with USD 3.5 million seed round

Pursuing a first-in-class therapeutic approach, Basel-based Mysthera plans to reshape the treatment landscape for autoimmune disease. PIM kinase inhibition uniquely and selectively modulates immune cell function in multiple lineages associated with complex disease. The company's pipeline includes pre-clinical stage, PIM kinase inhibitors in-licensed from Inflection Biosciences Ltd. Seed Capital from Forty51 Ventures will now help to advance the pipeline.

Autoimmune diseases impact over 23 million in US alone. Despite recent progress and novel treatment options, significant unmet needs remain due to poor response rates and adverse safety profiles of currently available treatment medicines.

Mysthera's founding management team and board of directors brings considerable experience, leadership and a successful track record across research and development.

"Leveraging our deep expertise in PIM kinase and immunology, we are pursuing a highly differentiated approach to tackle complex autoimmune diseases. We believe this will result in new treatments to change the lives of patients globally", said Darren Cunningham, co-Founder and Chief Executive Officer at Mysthera Therapeutics.

"PIM inhibition most critically hits effector B and T cells at the site of inflammation and inhibits their activation" added Dr. Stefan Haak, co-Founder and SVP R&D at Mysthera Therapeutics. "Our approach is uniquely positioned to also silence the essential cross-talk between these cells, impeding the pathogenic TLS formation associated with more erosive disease."

(Press release / SK)