CovalX and Bruker Announce Strategic Collaboration

This collaboration draws upon CovalX´s experience as a leader in providing novel tools and unique applications for intact protein-protein interaction and macromolecular analysis, and Bruker Daltonics´ cutting-edge life-science systems based on mass spectrometry (MS). By using CovalX’s High-Mass systems, Bruker customers will have access to the analysis of very high molecular weight molecules, with significantly improved detection capabilities in the 150-2000 kDa range. In conjunction with CovalX cross-linking kits for MALDI, the High-Mass system will give Bruker’s customers access to new applications such as intact therapeutic protein aggregates, antibody/antigen interactions and protein complex analysis.

Ryan Wenzel, CSO and Director of North American Operations at CovalX, commented: "This collaboration demonstrates CovalX´s commitment to increasing access to our high mass detection technology for all MALDI platforms, and to work with the manufacturers to find a solution for all customers. We believe the market for protein interaction analysis will continue to grow as it is on the leading edge of analytical development. Furthermore, we expect this growth to be fueled by the distinct advantages presented by the combination of our technologies.”

Bruker Daltonics is a leading supplier of life-science systems offering the growing proteomics research community a wide choice of MS-based research tools. Increasing the information content and understanding of protein complexes through the addition of stoichiometric data, inhibition, and aggregation, this molecular interaction data promises to offer new insights for protein researchers worldwide.

“With this strategic collaboration Bruker strengthens its market-leading position in the field of MALDI-TOF Mass Spectrometry by bridging the gap to new application fields in the analysis of protein complexes. The interaction of both CovalX and Bruker technologies will allow the customers to perform protein-protein interaction studies on an advanced level” said Ralf Schäfer – Global Product Manager MALDI TOF MS of Bruker Daltonics Life Science and Clinical Division (LSC).

CovalX is the market leader in intact protein complex analysis using high mass MALDI based technology with headquarters in Zürich, Switzerland and a North American subsidiary in Saugus, MA. CovalX was founded in 2006.